Dr. Elena Berger-Nicoletti


Office Tel.: +49 (0)6131 39 26139
Lab Tel.: +49 (0)6131 39 25743
Email bergerni(at)uni-mainz.de




Elena Berger-Nicoletti studied chemistry at the University of Rome ”La Sapienza" and obtained her laurea in chemistry with Prof. Mandolini in 1995. From 1996 to 2000 she worked on her PhD thesis in the field of supramolecular chemistry at the Technical University Munich under the supervision of Prof. Schmidtchen. After a Post-Doc at the Christian-Doppler laboratory in Vienna, Austria, working on improvements of the xanthate group analysis of viscose she is currently working at the University of Mainz with Prof. Frey. Her current research involves methodological development of MALDI-TOF-MS in the analysis of synthetic polymers.



Our research is focused on the application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to polymers in order to resolve analytical problems especially where other conventional methods failed to give satisfactory results. Another area is the investigation of new matrices based on inorganic-organic nanoparticles or polymer-nanoparticles, which are able to absorb the laser light. The new matrices will then be tested in the analysis of different synthetic polymers as well as relevant biological polymers.



[1] "Polyether-bridged cyclophanes incorporating bisphenol A units as neutral receptors for quats: Synthesis, molecular structure and binding properties" A. D. Cort, M. Nissinen, D. Mancinetti, E. Nicoletti, L. Mandolini, K. Rissanen, J. Phys. Org. Chem. 2001, 14, 425–431. DOI: 10.1002/poc.380.
[2] "Study of determination of substituent distribution of viscoses" T. Lange, E. Berger-Nicoletti, P. Kosma, A. Potthast, H. Sixta, Lenzinger Berichte 2003, 82, 102–106.
[3] "A Novel Method for Analysis of Xanthate Group Distribution in Viscoses" A. Rußler, T. Lange, A. Potthast, T. Rosenau, E. Berger-Nicoletti, H. Sixta, P. Kosma, Macromolecular Symposia 2005, 223, 189–200. DOI: 10.1002/masy.200550513.
[4] "Monofunctional metathesis polymers via sacrificial diblock copolymers" S. Hilf, E. Berger-Nicoletti, R. H. Grubbs, A. F. M. Kilbinger, Angew. Chem. Int. Ed. 2006, 45, 8045–8048. DOI: 10.1002/anie.200602323.
[5] "Pencil Lead as a Matrix for MALDI-ToF Mass Spectrometry of Sensitive Functional Polymers" E. Berger-Nicoletti, F. Wurm, A. F. M. Kilbinger, H. Frey, Macromolecules 2007, 40, 746–751. DOI: 10.1021/ma062458c.
[6] "Rod–coil copolymers from oligo(p-benzamide) foldamers" H. Seyler, E. Berger-Nicoletti, A. F. M. Kilbinger, J. Mater. Chem. 2007, 17, 1954–1957. DOI: 10.1039/B617598H.
[7] "Systematic investigation of functional core variation within hyperbranched polyglycerols" E. Barriau, L. Pastor-Pérez, E. Berger-Nicoletti, A. F. M. Kilbinger, H. Frey, S.-E. Stiriba, J. Polym. Sci. A Polym. Chem. 2008, 46, 2049–2061. DOI: 10.1002/pola.22539.
[8] "Incorporation of a Photosensitizer Core within Hyperbranched Polyether Polyols: Effect of the Branched Shell on the Core Properties" L. Pastor-Pérez, E. Barriau, E. Berger-Nicoletti, A. F. M. Kilbinger, J. Pérez-Prieto, H. Frey, S.-E. Stiriba, Macromolecules 2008, 41, 1189–1195. DOI: 10.1021/ma071661k.
[9] "Multihydroxyl-Functional Polystyrenes in Continuous Flow" C. Tonhauser, D. Wilms, F. Wurm, E. B. Nicoletti, M. Maskos, H. Löwe, H. Frey, Macromolecules 2010, 43, 5582–5588. DOI: 10.1021/ma902849r.
[10] "Rapid Synthesis and MALDI-ToF Characterization of Poly(ethylene oxide) Multiarm Star Polymers" M. Doycheva, E. Berger-Nicoletti, F. Wurm, H. Frey, Macromol. Chem. Phys. 2010, 211, 35–44. DOI: 10.1002/macp.200900377.
[11] "A Combined DPE/Epoxide Termination Strategy for Hydroxyl End-Functional Poly(2-vinylpyridine) and Amphiphilic AB 2 -Miktoarm Stars" A. Natalello, C. Tonhauser, E. Berger-Nicoletti, H. Frey, Macromolecules 2011, 44, 9887–9890. DOI: 10.1021/ma2023793.
[12] Supramolecular Linear- g -Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains" C. Moers, L. Nuhn, M. Wissel, R. Stangenberg, M. Mondeshki, E. Berger-Nicoletti, A. Thomas, D. Schaeffel, K. Koynov, M. Klapper, R. Zentel, H. Frey, Macromolecules 2013, 46, 9544–9553. DOI: 10.1021/ma402081h.
[13] "ABA Triblock Copolymers Based on Linear Poly(oxymethylene) and Hyperbranched Poly(glycerol): Combining Polyacetals and Polyethers" R. Klein, C. Schüll, E. Berger-Nicoletti, M. Haubs, K. Kurz, H. Frey, Macromolecules 2013, 46, 8845–8852. DOI: 10.1021/ma4015565.
[14] "Hydroxyfunctional oxetane-inimers with varied polarity for the synthesis of hyperbranched polyether polyols via cationic ROP" E.-M. Christ, S. S. Müller, E. Berger-Nicoletti, H. Frey, J. Polym. Sci. A Polym. Chem. 2014, 52, 2850–2859. DOI: 10.1002/pola.27315.
[15] "Living Polymer Chains with Predictable Molecular Weight and Dispersity via Carbanionic Polymerization in Continuous Flow: Mixing Rate as a Key Parameter" J. Morsbach, A. H. E. Müller, E. Berger-Nicoletti, H. Frey, Macromolecules 2016, 49, 5043–5050. DOI: 10.1021/acs.macromol.6b00975.
[16] "Methods of protein surface PEGylation under structure preservation for the emulsion-based formation of stable nanoparticles" L. Radi, M. Fach, M. Montigny, E. Berger-Nicoletti, W. Tremel, P. R. Wich, Med. Chem. Commun. 2016, 7, 1738–1744. DOI: 10.1039/C5MD00475F.
[17] "Silver Oxide Mediated Monotosylation of Poly(ethylene glycol) (PEG): Heterobifunctional PEG via Polymer Desymmetrization"
H. Pohlit, M. Worm, J. Langhanki, E. Berger-Nicoletti, T. Opatz, H. Frey, Macromolecules 2017, 50, 9196–9206. DOI: 10.1021/acs.macromol.7b01787.